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1

Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis

Ramis-Conde, Ignacio, Chaplain, Mark A J, Anderson, Alexander R A, Drasdo, Dirk

Journal:

Physical Biology

Year:

2009

Language:

english

File:

PDF, 900 KB

english, 2009

2

Biomechanical and Nutrient Controls in the Growth of Mammalian Cell Populations

HOEHME, STEFAN, DRASDO, DIRK

Journal:

Mathematical Population Studies

Year:

2010

Language:

english

File:

PDF, 851 KB

english, 2010

3

A quantitative high-resolution computational mechanics cell model for growing and regenerating tissues

Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Warmt, Enrico, Gonzàlez-Valverde, Ismael, Hoehme, Stefan, Grosser, Steffen, Kaes, Josef, Drasdo, Dirk

Journal:

Biomechanics and Modeling in Mechanobiology

Year:

2019

File:

PDF, 11.51 MB

2019

4

Modeling the interplay of generic and genetic mechanisms in cleavage, blastulation, and gastrulation

Dirk Drasdo, Gabor Forgacs

Journal:

Developmental Dynamics

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

5

Individual fates of mesenchymal stem cellsin vitro

Axel Krinner, Martin Hoffmann, Markus Loeffler, Dirk Drasdo, Joerg Galle

Journal:

BMC Systems Biology

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

6

Individual-based and continuum models of growing cell populations: a comparison

Helen Byrne, Dirk Drasdo

Journal:

Journal of Mathematical Biology

Year:

2009

Language:

english

File:

PDF, 933 KB

english, 2009

7

Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice

Albert Braeuning, Yasmin Singh, Benjamin Rignall, Albrecht Buchmann, Seddik Hammad, Amnah Othman, Iris von Recklinghausen, Patricio Godoy, Stefan Hoehme, Dirk Drasdo, Jan G. Hengstler, Michael Schwarz

Journal:

Histochemistry and Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010

8

On the Role of Physics in the Growth and Pattern Formation of Multi-Cellular Systems: What can we Learn from Individual-Cell Based Models?

Dirk Drasdo, Stefan Hoehme, Michael Block

Journal:

Journal of Statistical Physics

Year:

2007

Language:

english

File:

PDF, 3.75 MB

english, 2007

9

A single-cell-based model of tumor growth in vitro: monolayers and spheroids

Drasdo, Dirk, Höhme, Stefan

Journal:

Physical Biology

Year:

2005

Language:

english

File:

PDF, 1.62 MB

english, 2005

10

The virtual liver: a multidisciplinary, multilevel challenge for systems biology

Hermann-Georg Holzhütter, Dirk Drasdo, Tobias Preusser, Jörg Lippert, Adriano M. Henney

Journal:

Wiley Interdisciplinary Reviews: Systems Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

11

Mathematical modelling of liver regeneration after intoxication with CCl4

Stefan Höhme, Jan G. Hengstler, Marc Brulport, Marc Schäfer, Alexander Bauer, Rolf Gebhardt, Dirk Drasdo

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 5.22 MB

english, 2007

12

Liver regeneration after intoxication with CCl4: Spatial–temporal mathematical modelling in triple transgenic mice

Jan G. Hengstler, Dirk Drasdo, Rolf Gebhardt

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

13

Modeling the Influence of the E-Cadherin-β-Catenin Pathway in Cancer Cell Invasion: A Multiscale Approach

Ramis-Conde, Ignacio, Drasdo, Dirk, Anderson, Alexander R.A., Chaplain, Mark A.J.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

14

Modeling the Effect of Deregulated Proliferation and Apoptosis on the Growth Dynamics of Epithelial Cell Populations In Vitro

Galle, Jörg, Loeffler, Markus, Drasdo, Dirk

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 545 KB

english, 2005

15

From genotypes to phenotypes: classification of the tumour profiles for different variants of the cadherin adhesion pathway

Ramis-Conde, Ignacio, Drasdo, Dirk

Journal:

Physical Biology

Year:

2012

Language:

english

File:

PDF, 1.68 MB

english, 2012

16

How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis

Drasdo, Dirk, Hoehme, Stefan, Hengstler, Jan G.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 795 KB

english, 2014

17

Buckling Instabilities of One-Layered Growing Tissues

Journal:

Physical Review Letters

Year:

2000

Language:

english

File:

PDF, 102 KB

english, 2000

18

Scaling Laws and Similarity Detection in Sequence Alignment with Gaps

Drasdo, Dirk, Hwa, Terence, Lässig, Michael

Journal:

Journal of Computational Biology

Year:

2000

Language:

english

File:

PDF, 564 KB

english, 2000

19

The virtual liver: state of the art and future perspectives

Drasdo, Dirk, Bode, Johannes, Dahmen, Uta, Dirsch, Olaf, Dooley, Steven, Gebhardt, Rolf, Ghallab, Ahmed, Godoy, Patricio, Häussinger, Dieter, Hammad, Seddik, Hoehme, Stefan, Holzhütter, Hermann-Georg,

Journal:

Archives of Toxicology

Year:

2014

Language:

english

File:

PDF, 186 KB

english, 2014

20

[IEEE 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Lyon, France (2007.08.22-2007.08.26)] 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Shape Characterization of Extracted and Simulated Tumor Samples using Topological and Geometric Measures

Rohrschneider, Markus, Scheuermann, Gerik, Hoehme, Stefan, Drasdo, Dirk

Year:

2007

Language:

english

File:

PDF, 633 KB

english, 2007

21

COARSE GRAINING IN SIMULATED CELL POPULATIONS

Journal:

Advances in Complex Systems

Year:

2005

Language:

english

File:

PDF, 1.59 MB

english, 2005

22

EMERGENCE OF REGULATORY NETWORKS IN SIMULATED EVOLUTIONARY PROCESSES

DRASDO, DIRK, KRUSPE, MATTHIAS

Journal:

Advances in Complex Systems

Year:

2005

Language:

english

File:

PDF, 1.46 MB

english, 2005

23

Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones

Drasdo, Dirk, Hoehme, Stefan

Journal:

New Journal of Physics

Year:

2012

Language:

english

File:

PDF, 3.79 MB

english, 2012

24

Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance

Bertaux, François, Stoma, Szymon, Drasdo, Dirk, Batt, Gregory, Saucerman, Jeffrey J.

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 1.72 MB

english, 2014

25

TiQuant: software for tissue analysis, quantification and surface reconstruction: Fig. 1.

Friebel, Adrian, Neitsch, Johannes, Johann, Tim, Hammad, Seddik, Hengstler, Jan G., Drasdo, Dirk, Hoehme, Stefan

Journal:

Year:

2015

Language:

english

File:

PDF, 289 KB

english, 2015

26

DNA Sequence Alignment and Critical Phenomena

Drasdo, Dirk, Hwa, Terence, Lässig, Michael

Journal:

MRS Proceedings

Year:

1996

Language:

english

File:

PDF, 451 KB

english, 1996

27

Tumor cell load and heterogeneity estimation from diffusion-weighted MRI calibrated with histological data: an example from lung cancer

Yin, Yi, Sedlaczek, Oliver, Muller, Benedikt, Warth, Arne, Gonzalez-Vallinas, Margarita, Grabe, Niels, Kauczor, Hans-Ulrich, Breuhahn, Kai, Vignon-Clemental, Irene, Drasdo, Dirk

Journal:

IEEE Transactions on Medical Imaging

Year:

2017

Language:

english

File:

PDF, 2.37 MB

english, 2017

28

Modulating Portal Hemodynamics With Vascular Ring Allows Efficient Regeneration After Partial Hepatectomy in a Porcine Model

Bucur, Petru O., Bekheit, Mohamed, Audebert, Chloe, Othman, Amnah, Hammad, Seddik, Sebagh, Mylene, Allard, Marc-Antoine, Decante, Benoît, Friebel, Adrian, Miquelestorena-Standley, Elodie, Drasdo, Dirk

Journal:

Annals of Surgery

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

29

[IEEE 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) - Strasbourg, France (2016.10.29-2016.11.6)] 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) - Tumor microvasculature in lung cancer and diffusion-weighted MRI: Preliminary results

Yin, Yi, Sedlaczek, Oliver, Lotz, Johannes, Olesch, Janine, Breuhahn, Kai, Drasdo, Dirk, Vignon-Clementel, Irene E.

Year:

2016

File:

PDF, 392 KB

2016

30

Model Prediction and Validation of an Order Mechanism Controlling the Spatiotemporal Phenotype of Early Hepatocellular Carcinoma

Hoehme, Stefan, Bertaux, Francois, Weens, William, Grasl-Kraupp, Bettina, Hengstler, Jan G., Drasdo, Dirk

Journal:

Bulletin of Mathematical Biology

Year:

2018

Language:

english

File:

PDF, 6.21 MB

english, 2018

31

[IEEE 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) - Strasbourg, France (2016.10.29-2016.11.6)] 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD) - Quantitative estimation of tumor cellularity based on histology data

Yin, Yi, Sedlaczek, Oliver, Warth, Arne, Gonzalez-Vallinas, Margarita, Breuhahn, Kai, Vignon-Clementel, Irene E., Drasdo, Dirk

Year:

2016

Language:

english

File:

PDF, 467 KB

english, 2016

32

Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data

Jagiella, Nick, Müller, Benedikt, Müller, Margareta, Vignon-Clementel, Irene E., Drasdo, Dirk, Byrne, Helen

Journal:

PLoS Computational Biology

Year:

2016

Language:

english

File:

PDF, 8.75 MB

english, 2016

33

Estimating Dose Painting Effects in Radiotherapy: A Mathematical Model

López Alfonso, Juan Carlos, Jagiella, Nick, Núñez, Luis, Herrero, Miguel A., Drasdo, Dirk, Csikász-Nagy, Attila

Journal:

Year:

2014

Language:

english

File:

PDF, 3.32 MB

english, 2014

34

[IEEE 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI) - Venice, Italy (2019.4.8-2019.4.11)] 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019) - Automated Quantification of Amyloid Fibrils Morphological Features by Image Processing Techniques

Yin, Yi, Prigent, Stephanie, Torrent, Joan, Rezaei, Human, Drasdo, Dirk, Doumic, Marie

Year:

2019

Language:

english

File:

PDF, 212 KB

english, 2019

35

Gut microbiota maintains FXR activation and protects from fatal liver damage in a murine model of primary sclerosing cholangitis

Schneider, Kai Markus, Candels, Lena, Mohs, Antje, Elfers, Carsten, WahlstrÃ¶m, Annika, Liao, Lijun, Bennek, Eveline, Kilic, Konrad, Zaza, Ayham, Drasdo, Dirk, Zuehlke, Sebastian, Myllys, Maiju, Friss

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 441 KB

2020

36

Simulation of a detoxifying organ function: Focus on hemodynamics modeling and convectionâreaction numerical simulation in microcirculatory networks

Boissier, Noemie, Drasdo, Dirk, VignonâClementel, Irene E.

Journal:

International Journal for Numerical Methods in Biomedical Engineering

Year:

2020

File:

PDF, 20.58 MB

2020